process automation. The implementation of automation is a crucial enabling factor for the execution of experimental plans without the involvement of human operators. When coupled with suitable online analytics, optimization algorithms and a suitable model, such systems can autonomously find optimal experimental conditions. This contribution presents two illustrative examples of reactor setups from Ehrfeld Mikrotechnik[…]

potential, featuring recent studies on several areas of application: from synthesis to scale-up, quality analysis and crystallization. Abstracts from articles of interest were retrieved researching on scientific online resources, like Google Scholar and Pubmed, and the selection was made from year 2023 to year 2024 with the following keywords: flow chemistry applications, flow chemistry synthesis,[…]

for running azide chemistry. The gas phase concentration of hydrazoic acid above reaction mixtures must be monitored to avoid explosive concentrations. This can be done continuously by online Fourier transform infrared spectroscopy (FTIR) (8, 9).   The original process development by a former vendor who is not specialised in hazardous and especially azide chemistry relied[…]